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Brown, T.A., Tkachuk, A.N. and D.A. Clayton. Native R-loops persist throughout the mouse mitochondrial DNA genome. J. Biol. Chem. Epub ahead of print on 2008 Nov 5, doi:10.1074/jbc.M806174200.
Bonawitz,N.D., Clayton, D.A. and G.S. Shadel. Initiation and Beyond: Multiple Functions of the Human Mitochondrial Transcription Machinery. Mol. Cel. 24:813-825, 2006.
Brown, T.A., Cecconi, C., Tkachuk, A.N., Bustamante, C. and D.A. Clayton. 2005. Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism. Genes Dev. 19:2466-2476, 2005.
Larsson, N.-G., Wang J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G.S. and D.A. Clayton. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nature Genet. 18:231-236, 1998.
Lee, D.Y. and D.A. Clayton. RNase MRP correctly cleaves a novel R loop at the mitochondrial DNA leading-strand origin of replication. Genes Dev. 11:582-592, 1997.
Larsson, N.-G., Garman, J.D., Oldfors, A., Barsh, G.S. and D.A. Clayton. A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein. Nature Genet. 13:296-302, 1996.
Larsson, N.-G. and D.A. Clayton. Molecular genetic aspects of human mitochondrial disorders. Annu. Rev. Gen. 29:151-178, 1995.
Dairaghi, D.J., Shadel, G.S. and D.A. Clayton. Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator. J. Mol. Biol. 249:11-28, 1995.
Hess, J.F., Parisi, M.A., Bennett, J.L. and D.A. Clayton. Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 351:236-239, 1991.
Clayton, D.A. Replication and transcription of vertebrate mitochondrial DNA. Annu. Rev. Cell Bio. 7:453-478, 1991.
Parisi, M.A. and D.A. Clayton. Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 252:965-969, 1991.
Masters, B.S., Stohl, L.L. and D.A. Clayton. Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell 51:89-99, 1987.
Fisher, R.P., Topper, J.N. and D.A. Clayton. Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements. Cell 50:247-258, 1987.
Chang, D.D. and D.A. Clayton. A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA. Science 235:1178-1184, 1987.
Wong, T.W. and D.A. Clayton. In vitro replication of human mitochondrial DNA: Accurate initiation at the origin of light-strand synthesis. Cell 42:951-958, 1985.
Chang, D.D. and D.A. Clayton. Precise identification of individual promoters for transcription of each strand of human Cell 36:635-643, 1984.
Clayton, D.A. Replication of animal mitochondrial DNA. Cell 28:693-705, 1982.
Bibb, M.J., Van Etten, R.A., Wright, C.T., Walberg, M.W. and D.A. Clayton. Sequence and gene organization of mouse mitochondrial DNA. Cell 26:167-180, 1981.
Blanc, H., Wright, C.T., Bibb, M.J., Wallace, D.C. and D.A. Clayton. Mitochondrial DNA of chloramphenicol-resistant mouse cells contains a single nucleotide change in the region encoding the 3' end of the large ribosomal RNA. Proc. Natl. Acad. Sci. USA 78:3789-3793, 1981.
Van Etten, R.A., Walberg, M.W. and D.A. Clayton. Precise localization and nucleotide sequence of the two mouse mitochondrial ribosomal RNA genes and three immediately adjacent novel transfer RNA genes. Cell 22:157-170, 1980.
Gillum, A.M. and D.A. Clayton. Mechanism of mitochondrial DNA replication in mouse L-cells: RNA priming during the initiation of heavy-strand synthesis. J. Mol. Biol. 135:353-368, 1979.
Martens, P.A. and D.A. Clayton. Mechanism of mitochondrial DNA replication in mouse L-cells: Localization and sequence of the light-strand origin of replication. J. Mol. Biol. 135:327-351, 1979.
Bogenhagen, D. and D.A. Clayton. Mechanism of mitochondrial DNA replication in mouse L-cells: Introduction of superhelical turns into newly replicated molecules. J. Mol. Biol. 119:69-81, 1978.
Bogenhagen, D. and D.A. Clayton. Mechanism of mitochondrial DNA replication in mouse L-cells: Kinetics of synthesis and turnover of the initiation sequence. J. Mol. Biol. 119:49-68, 1978.
Bogenhagen, D. and D.A. Clayton. Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle. Cell 11:719-727, 1977.
Chang, A.C.Y., Lansman, R.A., Clayton, D.A. and S.N. Cohen. Studies of mouse mitochondrial DNA in Escherichia coli: Structure and function of the eukaryotic-prokaryotic chimeric plasmids. Cell 6:231-244, 1975.
Bogenhagen, D. and D.A. Clayton. The number of mitochondrial DNA genomes in mouse L- and human HeLa cells: Quantitative isolation of mitochondrial DNA. J. Biol. Chem. 249:7991-7995, 1974.
Clayton, D.A., Doda, J.N. and E.C. Friedberg. The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. Proc. Natl. Acad. Sci. USA 71:2777-2781, 1974.
Berk, A.J. and D.A. Clayton. Mechanism of mitochondrial DNA replication in mouse L-cells: Asynchronous replication of strands, segregation of circular daughter molecules, aspects of topology and turnover of an initiation sequence. J. Mol. Biol. 86:801-824, 1974.