Gene Myers' Home Page
Phone: (571) 209-4153 Fax: (571) 209-4083 Address: Janelia Farms Research Campus 19700 Helix Dr. Ashburn, VA 20147-2408
Recent Papers
Software
Curriculum Vitae (contact author for preprints)
Photo Album
Brief Bio
Gene Myers is one of the seven initial investigators to become a group leader at the new Janelia Farm Research Campus of the Howard Hughes Medical Institute. Gene comes to the JFRC from UC Berkeley where he was on the faculty of Computer Science from 2003 to 2005. He was formerly Vice President of Informatics Research at Celera Genomics for four years where he and his team determined the sequences of the Drosophila, Human, and Mouse genomes using the whole genome shotgun technique that he advocated in 1996. Prior to that Gene was on the faculty of the University of Arizona for 18 years and he received his Ph.D in Computer Science from the University of Colorado in 1981. His research interests include the design and analysis of algorithms for problems in computational molecular biology, discrete pattern matching and computer graphics, with a focus on building models of the cell and cellular systems from imaging data. He is best known for the development of BLAST -- the most widely used tool in bioinformatics, and for the paired-end whole genome shotgun sequencing protocol and the assembler he developed at Celera that put the data from such a project together. He has also written many seminal papers on the theory of sequence comparison. He was awarded the IEEE 3rd Millenium Acheivement Award in 2000, the Newcomb Cleveland Best Paper in Science award in 2001, and the ACM Kanellakis Prize in 2002. He was voted the most influential in bioinformatics in 2001 by Genome Technology Magazine and was elected to the National Academy of Engineering in 2003. In 2004 he won the International Max-Planck Research Prize and in 2005 was selected as one of two distinguished alumni (with David Haussler) at his alma-mater, the University of Colorado. In 2006 Gene was inducted into Leopoldina, the German National Academy and awarded an honarary doctorate at ETH, Zurich.Recent Papers ...
E. Myers,
``The Fragment Assembly String Graph,''
European Conf. on Computational Biology (Madrid, Spain, 2005), 79-85.
-
R. Edgar and E. Myers, ``PILER: identification and classification of
genomic repeats,''
Conf. on Intelligent Systems for Molecular Biology
(Detroit, Michigan, 2005), 52-58.
-
R. Sharan and E. Myers, ``A Motif-based Framework for Recognizing
Sequence Families,''
Conf. on Intelligent Systems for Molecular Biology
(Detroit, Michigan, 2005), 387-393.
- K. Rasmussen, J. Stoye, and E.W. Myers, ``Efficient q-Gram Filters for Finding All e-Matches Over a Given Length,'' 9th Conf. on Computational Molecular Biology (Boston, MA, 2005), to appear.
- G.M Landau, E.W. Myers, and M. Ziv-Ukelson, ``Two Algorithms for LCS Consecutive Suffix Alignment,'' 15th Combinatorial Pattern Matching Conference (Istanbul, Turkey 2004), 173-193. Published as Springer-Verlag Lecture Notes in Computer Science, #3109.
- H. Peng and E.W. Myers, ``Hybrid-GMM-Matching: Toward Comparing Embryogenesis Staining Pattern Images of D. melanogaster and Finding Co-Regulated Genes,'' 8th Conf. on Computational Molecular Biology (San Diego, CA, 2004), 157-166.
- S. Istrail, G.G. Sutton, ... (33 co-authors) ..., E.W Myers, and J.C. Venter ``Whole Genome Shotgun Assembly and Comparison of Human Genome Asssemblies'', Proc. Natl. Acad. Sciences 101 (2004), 1916-1921.
- M.D. Adams, G.G. Sutton, H.O. Smith, E.W Myers, and J.C. Venter ``The Independence of Our Genome Assemblies,'' Proc. Natl. Acad. Sciences 100, 6 (2003), 3025-3026.
- A.B. Carvalho, ... , M.D. Adams, E.W. Myers & A.G. Clark ``Y Chromosome and Other Heterochromatic Sequences of the Drosophila melanogaster Genome: How Far Can We Go?,'' Genetica 117 (2003), 227-237
- E. Myers and R. Durbin, ``A Table-Driven, Full-Sensitivity Similarity Search Algorithm," J. of Computational Biology 10, 2 (2003), 103-118. (Also appeared in: Proc. Workshop on Algorithms for BioInformatics (Rome, Italy 2002), 331-342.
- ``Sequence Comparison Algorithms in Molecular Biology,'' Tech. Rep. TR91-29, Dept. of Computer Science, U. of Arizona, Tucson, AZ (1991).
Software ...
- Press on the following link to get a compressed, tar file of the Anrep Pattern Matching System for specifying and searching for Protein and DNA sequence patterns. Consult the related article: ``A System for Pattern Matching Applications on Biosequences,'' with G. Mehldau, Computer Applications in the BioSciences 9, 3 (1993), 299-314.
- As a hobby around 1990, I did considerable work on the production of high-quality, real-time display of molecular images and include below a few sample visualization produced with my software just for the heck of it.
Sample Molecule Views |
|
 |
 |
Ball and Stick |
Space Filling |
 | |
Wire Frame | |
 |
 |
Solid Ribbon |
Wire Ribbon |